Link Between Sense of Smell and Alzheimer’s

Did you know that your sense of smell may be one of the earliest indicators of brain health? Researchers have found that changes in the ability to detect or identify odors can appear years — even decades — before memory loss or other cognitive symptoms of Alzheimer’s disease begin.

The reason lies in the brain’s anatomy. The olfactory bulb, which processes smells, is closely connected to the hippocampus and other regions responsible for memory and learning. In Alzheimer’s, these areas are often among the first to show signs of damage from beta-amyloid plaques and tau tangles. This is why a declining sense of smell is increasingly recognized as a potential early warning sign of cognitive decline.

Several studies have shown that people with reduced olfactory function are more likely to develop Alzheimer’s or other forms of dementia later in life. While losing your sense of smell doesn’t always mean you’ll develop Alzheimer’s, it’s a signal worth paying attention to — especially when combined with other risk factors. Researchers are even developing smell-based tests as simple, non-invasive screening tools for early detection.

The connection between smell and brain health also highlights the importance of monitoring subtle changes in our senses as we age. By being proactive — through regular medical checkups, healthy lifestyle habits, and supporting brain health with nutrition and cognitive care — we can take steps to reduce overall risk and promote long-term cognitive vitality.

In short, your sense of smell is more than just a way to enjoy your favorite foods or fragrances — it’s a window into the health of your brain. Paying attention to it may one day help us catch Alzheimer’s earlier, when interventions have the greatest impact.